ABSTRACT
A viral disease, COVID-19, is an emerging health threat to the public and has caused large-scale deaths throughout the world. Since its outbreak, scientists are working on sequencing its genome, understanding its targets, mechanism, and way of transfer from animal to humans. It is necessary to detect and prevent the disease outbreak at a large scale near to an early stage. This virus is visually characterized via electron microscopy, x-ray diffraction, and atomic force microscopy as well as can be detected in the laboratory through molecular assays, computed tomography (CT), biochemical tests, biomarkers such as an inflammatory biomarker, cardiac biomarkers, hepatic biomarkers, renal biomarkers, serological assays including enzyme-linked immunosorbent assay (ELIZA), lateral flow immunoassay, neutralization assay, luminescent immunoassay, rapid antigen assay, contact tracing, and potentially small molecule biomarkers in blood. In this chapter, we have summarized the possible methods for the detection and characterization of this new virus. Developing plug-and-play diagnostics to manage the COVID-19 outbreak may be helpful for prevention of ahead epidemics.
