ABSTRACT
The nose, by virtue of its centrofacial location, constitutes a focal point of interest to both the patient and injector. As such, overt skin pathology has often been addressed before the request for non-surgical rhinoplasty. There are, however, countless subtle and undiagnosed conditions that may have direct bearing on both injection safety and outcomes. The important prerequisite for non-surgical rhinoplasty is disease-free skin with good barrier function, as this is particularly important in avoiding late-onset adverse events. Before non-surgical rhinoplasty, disease-free skin with good barrier function is particularly important in order to avoid immune stimulation, infection and development of late-onset adverse events (LOAEs). Skin barrier disruption, which may be due to either infective or inflammatory conditions, predisposes to penetration of infective agents, thus posing a risk factor for LOAEs. Acne vulgaris is a common, multifactorial inflammatory disease of the pilosebaceous follicles affecting approximately 10% of individuals worldwide.
