ABSTRACT

This chapter offers a current overview of biomolecules of microbial origin applied in the treatment of bacterial infectious diseases and infers their potential for replacing antibiotics or serving as co-adjuvant therapies in such fights. As biomolecules for fighting pathogens responsible for infectious diseases, the most significant advantage of the use of AMPs relies on the fact that they possess a very reduced propensity to induce resistance due to their multiplicity of targets and lack of interaction with specific receptors. Although there are still no reports on the use of these bacterial origin biomolecules in the treatment of infectious diseases, their unique properties, and antibacterial features enhance their potential for future innovative therapies for treating infectious diseases. The search for alternatives to antibiotics has led researchers to investigate the antimicrobial potential of microbial origin biomolecules. All the alternatives presented have disclosed promising results that support their use in the treatment of infectious diseases.