ABSTRACT
This paper discussed some possible routes for the retrosynthesis of a specific sesquiterpene lactone in detail. Some differences between the routines are compared to select the best reaction pathway for it. Our main aim of the paper is the demonstration with details of three possible retrosynthesis routes of a specific sesquiterpene lactone from plants. All these routes are following the rule that simplifies the complex molecule into the simplest ones. Our designs don’t include the consideration of stereochemistry, while we are concentrated on the practicability of the routes, including the availability of the starting materials and stability of fragments. Finally, the comparison between the routes brings the best one. Our designs aren’t too innovative, but hopefully, they can provide or motivate more competitive and powerful ideas. The retrosynthetic routes design is the basis to reach the studies of undefined organic molecules, which is an essential tool for organic studies.
