ABSTRACT

Fullerenes attracted a lot of interest since their discovery in 1985 because of their unique cage-like structure. Fullerene is an allotropic form of carbon and has interesting and unique chemical and physical properties, which can be used for the development of various therapeutic and biomedical applications. In the last few decades, fullerenes have been widely studied for the drug delivery of anticancer drugs and development of targeted drug delivery systems. In this chapter, we aim to cover the recent developments in anticancer drug delivery systems based on fullerenes. This chapter can be of interest to the pharmaceutical and biotechnology community to provide the most recent advances on fullerenes as targeted anticancer drug delivery systems with therapeutic applications and challenges.