ABSTRACT

Background: Biotextiles are non-viable, persistent, or short-lived, fibrous textile frameworks made of synthetic or sustainable products that are used as a medical product in either an intrinsic or extrinsic biological environment for the mitigation, treatment, or prognosis of an injury or illness, and thus utilized to boost a patient’s health, serious illness, contentment, and wellbeing. The release of drugs through textile materials is a major means to enhance the quality of life for patients under severe medications. To create a medical textile with the ability to release drugs, such as a wound dressing, nanoparticle consisting of a drug in a synthetic or natural polymeric matrix can be used as an encouraging drug delivery system.

Recent findings: In recent years it has been found that these resources can be engineered to have the requisite rate of drug release in order to attain therapeutic efficacy. Textile-based drug releasing systems can be biocompatible, can be inert, can have high physical and mechanical properties, are effective for patients, are easy to implement, are inexpensive to manufacture, and are simple to disinfect.

Summary: Using novel drug-loaded fibres to develop nanotechnology-based drug release systems (DRSs) is a useful and appealing medical application of biotextiles. In this chapter, we will discuss relevant textile technologies, polymer types, and active pharmaceutical ingredients for the preparation of drug-loaded fibres. Future perspectives and areas for intensive DRS biotextiles research are also discussed.