ABSTRACT
Various types of plant mucilage available like alginic acid, gelatin maize starch and potato starch have been used as a binder in pharmaceutical formulation. But still finding a novel binder is useful in the pharmaceutical industry for manufacturing tablets. Lepidium sativum was chosen for its binding property. Lepidium sativum was found to be useful for the preparation of uncoated tablet dosage form. Lepidium sativum can be an alternative binder for the pharmaceutical formulations. Abundant availability, food grade status, economic feasibility, commercial suitability and reliability make the mucilage an alternative for the existing synthetic excipients. This chapter proposes to carryout formulation and evaluation of Lepidium sativum as an excipient in pharmaceutical formulation. It shows the effect of Lepidium sativum as binder in the formulation development of aspirin and ibuprofen tablets in comparison with the standard binders. Lepidium sativum has a better binding capacity in comparison with polyvinyl pyrrolidine.
