ABSTRACT

Neural sensing amplifiers are essential blocks for acquiring bio-signals in neuroscience and clinical research for treating a variety of diseases related to neural disorders. Such amplifiers are used to extract and condition micro-to millivolt scale signals aroused from weak neural activities. As such, they typically have ultra-low noise level as they usually dominate the noise level of front-end sensing blocks. Further, miniaturized neural amplifiers based on integrated circuits offer benefits of small form factors and ultra-low power consumption, allowing unobtrusive operations and minimum tissue heat dissipation. They are, hence, gaining popularity rapidly for wearable and implant applications. This chapter discusses example designs and circuit considerations for low-power and low-noise neural sensing amplifiers suitable for portable and implantable medical devices.