ABSTRACT

Drugs and radiation can affect cell cycling and may lead to alopecia. In recent decades, with the advent of novel therapies such as biologics and immunomodulating agents, the number of medications associated with alopecia has markedly risen. This chapter reviews drugs that have been implicated in hair loss and explores the mechanisms of how pharmaceutical agents and radiotherapy can alter hair cycling and structure. A review of prevention and management strategies for drug-induced alopecia is also provided.