ABSTRACT

Lipids are important energy and structural compounds. Their decomposition provides a significant amount of energy needed for various life processes. Together with proteins, they form the most important structural elements of cells and cell organelles, while others are precursors for the synthesis of numerous active compounds such as some hormones or prostaglandins. In the circulation, lipids are found packed in lipoprotein molecules. Lipoproteins have a central lipid part (core) in which there are triglycerides and cholesterol esters, and on the surface there is an envelope composed of certain proteins (apoproteins), phospholipids, and small amounts of free cholesterol. Due to the action of various noxious effects of fetal life (in utero), lipid peroxidation occurs, i.e., cell damage, which becomes the basis for the onset of the disease.