ABSTRACT
Biosensing is a growing domain, but the primary challenge is in developing smaller and smaller-sized microchips for efficient detection using a very small sample size. In this respect, the introduction of complementary metal oxide semiconductors (CMOS) has emerged as a boon, which extensively offers possibilities of downsizing the microchip while delivering high efficacy performance. The prominent applications of CMOS sensors can be extensively observed from phones and laptops to various biological domains. This chapter extensively discusses the importance of CMOS integration to the biosensor domain and the various factors associated with it like the circuitry, fabrication scheme, and result extraction.
