ABSTRACT

With the increase of antimicrobial resistance cases, researchers are now looking into alternative compounds with antimicrobial activity. Among these, polypeptides derived from microbes are compounds that have antioxidant, antidiabetic, antihypertensive, and immunomodulatory activity and antimicrobial property. Many plant- and animal-derived matrices, such as milk, fish, cereals, vegetables etc., have been used for the preparation of bioactive peptides after fermentation by suitable strains of bacteria, fungi, and yeast. This chapter provides an overview on the structure and properties of polypeptides, the mechanism behind their preparation, and their potential applications in human health.