ABSTRACT
Enzyme-based biopharmaceuticals are a rapidly emerging sector that explores and exploits microorganisms and their products for therapeutic applications. Microbial enzymes are exceptional biocatalysts that regulate the rate of biochemical reactions, producing remarkable usable products. They carry numerous outstanding features such as catalytic potential, high substrate specificity, and pH and temperature optima. Due to these unique attributes, they find divergent clinical applications. They are being increasingly exploited for the treatment of a wide spectrum of diseases, either alone or in combination with other therapies. Microbial enzymes offer diverse advantages, including ease of isolation, high consistency, higher yields, economic feasibility, high stability, and also the processes of product modification, as well as optimization are easier for microbial enzymes. Thus, microbial enzymes display fascinating features and opportunities, and they form an important subclass of modern biopharmaceuticals. In this chapter, we focus on the curative potential of microbial enzymes, including enzybiotics, digestive aids, anti-inflammatory, anticancer, and fibrinolytic agents, as well as potential involvement in sensing applications. This information will help to highlight and further explore their therapeutic potential, which is fast gaining popularity and assisting healthcare.
