ABSTRACT

The wounds can be treated by using dressings, antibiotics, and skin replacements and growth factor therapy. Wound-healing dressings effectively promote and help to provide a favorable milieu, which is conducive to the healing process. Many factors can obstruct one or more phases of wound healing, resulting in inadequate or impaired tissue recovery. Many natural and synthetic polymers are being used in the preparation of artificial dressing materials. The biopolymers such as alginate, collagen, chitosan, gelatin cellulose starch, and other polysaccharides based as well as protein, and lipid-based hydrogels. have been widely investigated as materials for wound dressings. Alginic acid is a polymer that derives from brown algae like Laminaria and Ascophyllum. Linear block copolymerization of D-mannuronic acid and L-guluronic acid produces alginic acid. Alginic acid and salts are used to treat wounds and burns because of their hemostatic properties. Due to their availability, superior biological capabilities, and low toxicity, they are biomaterials in the field of wound care management. When alginate dressings come into contact with a wound, they turn into a gel. The 324intrinsic features of alginic dressings depend on the ions in wound exudates. The absorbent properties of alginate hydrogels are determined by this cation interaction, which facilitates their usage as a dressing. The expansion of the hydrogel creates a moist environment healing the wound, while also preventing it from microbial invasion