ABSTRACT
DNA double helix, commonly known as a macromolecule, is a biopolymer. The present chapter focuses on its mechanical properties at the microscopic level. Further, different theoretical and computational methods along with experimental techniques are discussed to determine these properties. The structural transitions of DNA under force, ionic effects, and protein binding effects on elastic properties of DNA are also reviewed. An alluring future perspective of this exciting topic on nanotechnology, nanoelectronics, and clinical research are also be discussed.
