ABSTRACT

The current review discusses the traditional information and pharmacological features of the most important medicinal species that are the focus of this study. The selected species for the present review belongs to the 90family Rutaceae which comprises the most medicinally important sources of secondary metabolites, mainly such as flavonoids, alkaloids, limonoids, coumarins, essential oils, and volatile oils. The main purpose of this review study is to look in to the more recent developments in the phytochemical and pharmacological investigation of this family as well as the traditional uses of its species in a systematic way. The species belongs to this family known for largest numbers of secondary metabolites. Other species in this family have, however, been the subject of pharmacological investigations. The species comprises a wide range of biologically active chemical compounds such as antibacterials, anticoagulants, and anti-carcinogens in it. Accordingly, anti-inflammatory, antihyperlipidemic, antidepressant, antibacterial, antiviral, anthelmintic, antifungal, insecticidal, antiprotozoal, cytotoxic, and antioxidant effects of the species of family Rutaceae considered here. This current paper provides an overview of its traditional, phytochemical, and pharmacological features, which may aid researchers in determining the potency and efficacy of Family Rutaceae as therapeutic plants.