ABSTRACT
After tooth extraction, the injury will form in the surrounding tissue, triggering the body's response to start the process of healing. Honey has antibacterial, antiinflammatory, and antioxidant properties that can accelerate wound healing. The purpose of this study was to determine the effectiveness of forest honey (Apis dorsata) and livestock honey (Apis cerana and Trigona) on the number of fibroblasts in wound healing after tooth extraction in Wistar rats. This study was conducted by counting the number of fibroblasts on every histological preparation of Wistar rats after revocation treatment to the negative control group without treatment, the positive control group by giving iod glycerin, the Apis dorsata honey group, the Apis cerana honey group, and the Trigona honey group. The result of statistical analysis using a one-way ANOVA test showed a significant difference in the increase in the number of fibroblasts in all groups treatments. The result of Duncan's test showed that the Trigona honey group was significantly different from all other treatment groups. The most effective honey in increasing the number of fibroblast cells in wound healing after tooth extraction of Wistar rats was Trigona honey.
