ABSTRACT
The sixteenth leading cause of mortality worldwide is oral cancer. Based on the type, location, and stage, there are several treatment options for oral cancer, including chemotherapy, radiotherapy, surgery, or a combination of these. However, it is important to take into account the possibility of adverse effects brought on by high medicine dosages and uneconomical costs. As research indicates, plants have been a significant source of anticancer chemicals. A plant named Elephantopus scaber Linn is said to have anticancer properties. This review aims to discover the potentials of E. scaber L. as a candidate against oral squamous cell carcinomas (SCC). References were discovered by searching PubMed for the terms “anticancer” and “Elephantopus scaber” between 2000 and 2022. For this review, only English references were taken into account. E. scaber L. has been used traditionally as a treatment in many countries. Additional pharmacological activity associated with E. scaber includes anticancer, antioxidant, antidiabetic, antibacterial, and anti-inflammatory characteristics. Despite the fact that there is still much to understand about E. scaber and its therapeutic potential as an anticancer agent, it has tremendous potential against cancer. To investigate its potential as a candidate against oral cancer, more research on E. scaber's anticancer activities against oral squamous cell carcinomas (SCC) is needed.
