ABSTRACT
This chapter presents a case study of a A 22 year old white man, who died on June 6, 1978, had been well until about July 15, 1977 (12 months before death), when, while a student at college, he noted weakness in both legs, especially when climbing stairs. The weakness progressed to involve the arms, and paresthesias appeared in his feet, hands and arms. Clinical and morphologic findings are described in a 22 year old man with prolonged thrombocytosis, and coronary and splenic arterial thrombi causing myocardial and splenic infarcts. The absence of preexistent extensive coronary atherosclerosis, the presence of thrombus in more than one epicardial artery and in multiple intramural coronary arteries, the presence of arterial thrombosis in a noncoronary artery (splenic) and the absence of another apparent cause of the arterial thromboses are evidences that the intraarterial clotting in this patient was related to the severe thrombocytosis.
