ABSTRACT

This chapter presents a case study of a 22-year-old man with fatal congestive heart failure almost a year after a large MI associated with thrombocytosis. Although thrombocytosis may cause vascular thrombosis with resultant organ or tissue ischemia, the occurrence of coronary thrombosis and myocardial infarction (MI) in this circumstance is rare. To our knowledge, this association has been reported only once previously, in a 22-year-old man. At that time, he underwent embolectomy of the left brachial and radial arteries and the LV aneurysm in the anterior wall was excised. The aneurysm contained thrombus. CHF persisted and he was hospitalized several times. The platelet counts ranged from 400,000 to 800,000/mm3. The final hospital admission at age 22 years was necessitated by severe CHF and ischemia of the distal left fourth finger. Cardiac output and blood pressure diminished progressively and the patient died 10.5 months after the acute MI.