ABSTRACT

This chapter presents the necessary theoretical background of Small angle neutron scattering (SANS), provide the relevant experimental details, and describe data analysis procedures so that it is self-contained and sufficient as a guide for new investigations. SANS experiments provide significant information with nm-resolution on spatial morphology in a quantitative manner, as the scattered intensities are determined by the spatial concentration distribution in a sample. A SANS experiment is performed in large-scale facilities through a proposal evaluation procedure. Soft matter nanostructures may arrange differently at different length scales giving rise to hierarchical structures. Interactions of proteins with polyelectrolytes, mainly of electrostatic nature, lead to self-organized structures in aqueous media. SANS has been proven a powerful method for the investigation of soft materials and biomaterials. SANS will definitely accompany cutting-edge research and discoveries in new bionano-formulations for the next decades.