ABSTRACT
Alzheimer’s disease (AD) is a complex neurodegenerative disorder characterized by progressive cognitive decline and memory loss. Currently, there is no known cure for AD, and available treatments have limited efficacy. Natural products derived from diverse natural sources offer a potential approach for the development of novel therapeutics. Computational techniques, such as molecular docking, virtual screening, and molecular dynamics simulations, enable the identification and characterization of natural compounds that interact with key targets implicated in AD pathology. This chapter provides an in-depth exploration of the utilization of natural products and their mechanisms of action in combating AD. Additionally, the chapter investigates computational methodologies such as molecular docking, virtual screening, and network pharmacology analysis, which facilitate the identification and characterization of natural compounds that interact with critical targets implicated in AD pathology. This comprehensive understanding of therapeutic applications of natural products, achieved through computational approaches, holds great promise for the advancement of effective AD treatments.
