ABSTRACT
The compelling increase rate of diseases is a quest of concern for medical professionals. The gigantic burden is the focal point of all the possible etiologies for the causation of diseases. One such etiology is the Gene affected. In the past five years, numerous groundbreaking research has been concerned with epigenetics. It is now well understood that the gene itself is not responsible for the disease causation, but its expression without any change in underlying DNA sequence also has emerged as a vast field of study for research. The naturally occurring polyphenolic compounds – flavonoids are celebrated to contribute well to the treatment of various diseases and also to prevent the side effects caused by various treatment modalities. The pace at which the regulation of genes can be made “naturally” is a topic of concern for all researchers and biologists around the globe.
