ABSTRACT

In the current environmental crisis era, manufacturing significant biotechnological products employing supportable biological techniques has become well-known. It appears to be undesirable in the case of industrial yield dependent on downstream processing (DSP) of bio-catalyst products, which leads to an increase in the DSP rate. When combined with a highly selective bio-catalyst-based technique, whole-cell bio-catalysis could represent a significant advantage over chemical processes. When compared to the highly selective bio-catalysis-based approach, which might affect the process and 556purification of industrial goods, the whole-cell system is more promising. The advancement of whole-cell bio-catalysis has increased its acceptance as a green process because the reaction is carried out via a biological approach. Industrial microbial products are widely employed due to their ease of use and the fact that they use renewable bioresources as feedstock. The DSP is vital to the economic sustainability of the product on the commercial platform. The manufacturing, DSP, recovery, and purification procedures of the various products produced via whole-cell bio-catalysis and fermentation are discussed in this chapter.