ABSTRACT

Chemical industries have thrived for decades on non-renewable resources and non-biological catalytic methodologies. Chemically catalytic processes are 72laborious and cost intensive. Biocatalysis confers the ability to perform the reactions at ambient environmental conditions and is eco-friendly with costeffective in nature. The plethora of information on designing the whole-cell as a catalyst has paved the way to be recognized at an industrial level. The history of using cellular systems for obtaining various chemicals is long known and is now pursued for sustainable developments in the field of biocatalysis. Chemicals pertaining to their origin of synthesis and the process involved together contribute to the greener processes for their synthesis. Whole-cell biocatalysts are novel entities, and this chapter contributes towards compiling the type of metabolic networks involved in the synthesis of a particular chemical derived from a microbe. The strategies involves increased production using low-cost, sustainable, and renewable raw materials, bypassing the need for harmful inorganic catalysts or harsh production processes. This chapter gives insights into production strategies of industrially valuable chemicals via greener technology, whole-cell biocatalysis (WCB).