ABSTRACT
In the golden age of pharmaceutical nanocarriers, the original ideas and concepts are reaching their full potential. Over the past few decades, several nanoparticulate formulations have been designed and evaluated at the preclinical and clinical levels for the delivery of drugs. A revolution in the scientific community has been sparked by recent rapid advancements in the capability to generate nanoparticles of uniform size, shape, and composition. Liposomes are vesicular structures that are closed on both sides and are made up of bilayers of hydrated phospholipids. Solid liquid nanoparticles (SLNs) that are made up of fully crystallized lipid components have a highly organized crystalline structure that contains emulsifiers and are characterized by having the medication incorporated into it. The formation of liquid crystalline formations by the spontaneous self-assembly of certain lipids presents an opportunity for the development of a new category of sustained release matrix.
