ABSTRACT
Heritability is commonly used as a population-based risk assessment for acquiring a certain ailment because it provides preliminary information on risks through the use of inherited diseaselinked genes that are expressed in genes that cause neurological dysfunction. The structural fluctuations that make these proteins susceptible to misfolding and cause them to build up in neurons are caused by a variety of genetic abnormalities. Lately, scientists have focused on neuro-immunity as yet another significant hypothesis in the pathogenicity of neurological disorders. The brain has 182extremely complex immune regulation, which is closely linked to the peripheral immune system. The capability of the immune system and the central nervous system (CNS) to interact with one another is essential for developing effective immunity to injury and infection, sustaining psychological health, and shaping behavioral patterns. Gene expression may hold the key to answering one of the important unaddressed concerns in neurodegeneration research: the regional favorable impairment of neurons within the nervous system. The potential to use genetic factors to form therapeutic approaches arises from a deeper understanding of the heritability underlying neurological disorders.
