ABSTRACT

In the past decades, imaging has become more important in biomedical sensing applications for healthcare because it provides non-invasive nature, wide ranges of anatomical structure and physiological sensing, and potential for real-time continuous monitoring. Conventional biomedical imaging techniques include X-ray and X-ray-based computed tomography (CT), ultrasound, magnetic resonance imaging (MRI), optical imaging, positron emission tomography (PET), and single-photon emission computerized tomography (SPECT). Combined with these modalities, imaging contrast agents play a key role in building a bridge between external detectors and internal biological/pathological processes. In recent years, novel imaging techniques such as multi-modal imaging have been fast developed to fulfill the gaps between needs and limitations in the conventional modalities. Meanwhile, new imaging contrast agents are quickly emerged and covered in broader bio-sensing applications. This chapter covers current cutting-edge imaging techniques, particularly, current imaging contrast agents and systems for a variety of biomedical sensing.