ABSTRACT

Recent studies have stressed oxidative stress and lipid peroxidation, insulin resistance, mitochondrial dysfunction, adipokines, and proinflammatory cytokines in the progression and establishment of NAFLD. Further evidence also suggests an association between MetS and NAFLD. The pathogenesis of MetS and NAFLD are observed to have similar and common pathophysiological processes, with the primary focus on insulin resistance. “Non-alcoholic fatty liver is the object of significant scientific and clinical interest which is going to increase in the following years. Epidemiological studies demonstrate that NAFLD and MetS are emerging as major problems of public health. Hence, a reliable, non-invasive method has long been sought to diagnose NAFLD, to assess the degree of fibrosis, and which allows for a less invasive and stressful assessment of the course of the liver. With this background, the present research is aimed to study Non-alcoholic fatty liver disease (NAFLD).”