ABSTRACT

Over the past four decades, the diagnosis and management of children with various malignancies have improved tremendously. As a result, an increasing number of children are long-term cancer survivors. With improved survival, however, has come an increased risk of treatment-related cardiovascular complications that can appear decades later. These problems are serious enough that all caregivers of childhood cancer survivors, including oncologists, cardiologists, and other healthcare personnel, must pay close attention to the short- and long-term effects of chemotherapy and radiotherapy in these children. This chapter discusses the effects of treatment-related cardiovascular complications from anthracyclines and radiotherapy, and the methods for preventing, screening, and treating these complications.