ABSTRACT

Sebaceous tumors are uncommon adnexal neoplasms including two types of benign tumors, sebaceous adenoma and sebaceoma, and one malignant tumor, the sebaceous carcinoma. Benign sebaceous tumors commonly involve the head and neck region of elderly individuals and appear as solitary slow-growing lesions, while sebaceous carcinoma mainly involves the ocular adnexa. Multiple forms of sebaceous tumors in younger individuals are distinctive markers of the Muir-Torre syndrome, which is an autosomal dominant genetic disease and represents an allelic variant of the hereditary nonpolyposis colon syndrome. On dermoscopic examination sebaceous tumors are frequently characterized by yellow structures and unfocused arborizing vessels. Neither the clinical nor the dermoscopic appearance allow in most cases the differentiation of the different types of sebaceous tumors. However, two patterns have been described for benign sebaceous tumors, with and without a central crater, while sebaceous carcinoma is generally characterized by a yellow background, polymorphous vessels and ulceration.