ABSTRACT

Abstract ................................................................................................. 124 5.1 Introduction .................................................................................. 124 5.2 Biological Characteristics ............................................................ 125 5.3 Diseases ....................................................................................... 125 5.4 Epidemiology ............................................................................... 126 5.5 Genomics ..................................................................................... 131 5.6 Pathogenesis ................................................................................. 132 5.7 Identification and Detection ......................................................... 139 5.8 Treatment and Prevention ............................................................ 140 5.9 Future Perspectives ...................................................................... 144 Keywords .............................................................................................. 144 References ............................................................................................. 144

XIN-HE LAI1,2,#*, LONG-FEI ZHAO1#, and YAN QIAN2*

1College of Life Sciences, Key Laboratory of Plant-Microbe Interactions of Henan, Shangqiu Normal University, 55 Pingyuanzhong Road, Shangqiu, Henan, PR China 476000

2Department of Pediatrics, the First Affiliated Hospital of Wenzhou Medical University, New Campus at Nanbaixiang, Ouhai District, Wenzhou, China 325000

*Corresponding author. E-mail: laixinhe@yahoo.com; qianyan11@126.com

ABSTRACT

Enterotoxigenic Escherichia coli (ETEC) is one of the causal agents of diarrhea, most frequently seen in children in the developing world. This chapter reviews how people get into contact with ETEC, its transmission pathway in the body, and the up-to-date understanding of ETEC’s pathogenic mechanism(s) to make human sick and cause diarrhea. The introduction of these basic knowledges hopefully will serve the purpose steering people from the risk of contracting ETEC-related diseases and edging responsible institutions to further improve access, quantity, and quality of public health facilities to curtail the threat of ETEC.