ABSTRACT

The aim of this study was to report the adverse effects of common antituberculosis drugs such as pyrazinamide, rifampicin, isoniazid, and ethambutol in a diabetic patient. LHL, a 40-year-old Chinese man weighing 55 kg, presented with symptoms of low appetite, polydipsia, polyuria, polyphagia, and coughing up white sputum (sometimes with blood), and night sweats. He had neither shortness of breath, nor chest pain; however, his breath produced sound. He smoked two to three cigarettes/day for 10 years, was unemployed, and has been socially involved in prostitution for the last 7 years, but with negative HIV and syphilis tests. He had a history of untreated hypertension 5 years ago and no known drug allergy. Diabetic ketoacidosis and positive acid-fast bacilli tests were positive. Antituberculosis, anti-hypertensive, and oral antidiabetics were given previously instead of insulin injection. Finally, ethambutol was not prescribed during his discharge because he suffered from blurred vision.