ABSTRACT
Honey vinegar is a well-known traditional medicine used for preventing hyperlipidemia. Therefore, this study aimed to prove the efficacy of honey vinegar as an alternative herbal medicine to treat hyperlipidemia in rats (Rattus norvegicus). A total of 30 rats were divided into three groups: negative control, positive control, and test groups. The negative control group was given demineralized water. The positive control group was given fried oil (4 ml/kg BW) and pork oil (5 ml/kg BW) orally. The test group was given fried oil (4 ml/kg BW), pork oil (5 ml/kg BW), and honey vinegar (10 ml/kg BW) orally. Each group underwent the respective therapy for 14 days. On the 15th day, the LDL-cholesterol, HDL-cholesterol, triglyceride, and total cholesterol levels of all the groups were tested. The results demonstrated that the test group treated with honey vinegar had lower cholesterol levels (P < 0.05). Therefore, it can be concluded that honey vinegar has good efficacy in reducing hypercholesterolemia in rats.
