ABSTRACT
Coronaviruses are enveloped virus with a positive-sense single-stranded RNA genome and a nucleocapsid of helical symmetry. Coronaviruses are named due to the appearance by electron microscopy which resembles a crown or halo created by viral spike peptomers that determine the virus tropism. The hemagglutinin-esterase protein is present in a subset of ß-coronaviruses and binds sialic acids on surface glycoproteins and contains acetyl-esterase activity. Mortality is highly witnessed in the geriatric population and the underlying comorbidities include cardiac and respiratory disorders and immunosuppressed states. Several acute neurological syndromes have been associated with coronaviruses. Supportive therapy should include prevention of deep vein thrombosis since patients are hypercoagulable and may have endothelial cell damage. Due to lung involvement, patients are hypoxic for prolonged periods of time and may lose their hypoxic drive making it more critical to intubate sooner and may require prolonged intubation.
