ABSTRACT

Sperm DNA fragmentation is a broad concept that involves various situations where DNA sequence integrity in sperm is affected, linked to specific techniques developed to detect and quantify it.

In recent decades, the rapidly evolving field of assisted reproduction techniques together with technical developments concerning therapeutic interventions has increased the need to improve diagnostic tools to estimate pregnancy chances or forecast reproductive outcomes. Moreover, the availability of appropriate diagnostic tools may positively impact reproductive success by avoiding repeated failures or offspring with health problems.