ABSTRACT
Aneuploidy is the most common genetic abnormality in human embryos. Preimplantation genetic testing for aneuploidy (PGT-A) can increase pregnancy rates in infertile couples requiring assisted reproductive technology (ART). This technique has also been called preimplantation genetic screening (PGS) and comprehensive chromosome screening (CCS), among other names. Large datasets from comprehensive aneuploidy testing of preimplantation embryos demonstrate that over half of embryos produced by in vitro fertilization (IVF) are aneuploid [1-3]. Several techniques have been applied for aneuploidy screening and embryo selection in IVF, including screening procedures for numerical or structural chromosome abnormalities.
