ABSTRACT
Preimplantation genetic testing (PGT) is an alternative to prenatal diagnosis for those couples with known risk of transmitting a genetic condition to their offspring. Oocytes and/or preimplantation embryos obtained by in vitro fertilization (IVF) are analyzed and only those embryos free of the disorder under study are transferred to the uterus to achieve pregnancy. The main advantages of PGT are (1) to circumvent invasive prenatal diagnosis, which is frequently followed by the difficult decision of pregnancy termination if results are unfavorable, and (2) to try to increase the likelihood of having an unaffected pregnancy by selecting from multiple embryos.
