ABSTRACT
Medulloblastoma is a fast-growing malignant tumor that is separated by the 2016 WHO classification of central nervous system (CNS) tumors into three categories: medulloblastoma genetically defined; medulloblastoma histologically defined, and medulloblastoma NOS. Possibly arising from a common precursor cell of the subependymal matrix in the CNS, embryonal tumors are a heterogeneous group of malignant brain lesions that consist of hyperchromatic cells and subarachnoid space. Medulloblastoma usually forms in the posterior fossa of the cerebellum, with 80" of tumors in children found in the vermis of the cerebellum and 50" of tumors in adults involving the cerebellar hemispheres. Medulloblastoma is the most common embryonal tumor in children of up to 4 years of age and represents an important cause of death in children older than one year in the developed world. Preliminary diagnosis of medulloblastoma is possible through CT and MRI assessment of the entire brain and spine, with and without contrast enhancement.
