ABSTRACT
Three main enzymes involved in the enzymatic antioxidant system include superoxide dismutase (SOD), catalase, and glutathione peroxidase. SODs are highly inducible enzymes, and are important targets for many antioxidant nutraceuticals. Green tea is one of the most extensively studied antioxidant nutraceuticals for cancer prevention. However, more research work especially clinical trials need to be performed for the safe and effective use of antioxidant nutraceuticals against prostate cancer. The diagnosis of Benign prostate hyperplasia (BPH) and prostate cancer is based on the evaluation of lower urinary tract symptoms (LUTS), digital rectal examination and physical examination, urinalysis, and the presence of the prostate specific antigen, and urinary frequency and volume. BPH is one of the leading causes of urinary dysfunction in men. The α1-Adrenergic receptor blockers have been the mainstay of BPH therapy for decades. If LUTS is bothersome, pharmacotherapy along with modifying fluid and food intake is the standard of treatment.
