ABSTRACT

This chapter discusses advances in treatment verification and delivery techniques in radiation therapy of lung cancer. Evaluation studies were also performed on a limited number of lung cancer patients. The Calypso® System is a commercial device which has been developed and used for target localization or tracking for prostate and lung cancer treatments. Phase-matched dgital tomosynthesis (DTS) as been developed recently to address the effect of respiratory motion on lung tumor localization using DTS. Phase-matched DTS matches the motion-blurring pattern in reference and on-board DTS images by matching the phases of the digital reconstructed radiographs used for reference DTS econstruction with those of the on-board projections used for on-board DTS econstruction. The lack of full three-dimensional (3D) information may impair the localization accuracy of DTS when there is soft-tissue deformation of the patient. DTS is a technique to reconstruct quasi-3D images using two-dimensional cone beam x-ray projections acquired only within a limited scan angle.