ABSTRACT

The general approach to exposure assessment for epidemiological studies is significantly different from that generally used by industrial hygienists to assess the presence of a recognized hazard by the use of exposure limits, The principal source of this difference is that the epidemiologic study is performed to detect a hazard and determine the nature of any dose-response relationship, whereas compliance testing is performed with the presumption that the dose-response relationship is known and built into the exposure limit. These differences have important implications for sampling strategy.