ABSTRACT

Edward jenner meticulous methodology led to numerous scientific breakthroughs, the most significant being that of the relationship between cowpox and smallpox. His work led to the discovery and implementation of a vaccine against smallpox, one of the leading causes of death and disfigurement during his time, laying the foundation for the total eradication of the disease in 1980. When he was 23 years old, Jenner re-established himself in Berkley and pursued his interest in the natural world, keeping meticulous notes of his observations and frequently corresponded with Hunter about his various hypotheses. In Jenner’s local community, it had long been believed that milkmaids who contracted cowpox from cows were not affected by the smallpox virus. Jenner’s theories on vaccination were met with scepticism from many. It must be remembered, however, that vaccination was introduced into a society where little was known about the spread and cause of disease.