ABSTRACT

Globally, growing populations and longer mean life spans are leading to a large aging population. This demographic shift comes together with an increased global incidence of non-communicable diseases (NCDs), especially the incidence rate of neurodegenerative diseases in the elderly population. Neurodegenerative diseases include the chronic exposure to oxidative stress and inflammation, loss of protective signaling, and the accumulation of toxic proteins. Tree nuts are dry fruits with one seed in which the ovary wall becomes hard at maturity. Nutrients are bioactive molecules that are essential for human health and functioning. Most cannot be synthesized by the human body and need to be obtained from food. Natural antioxidants present in foods include vitamins, minerals, carotenoids, and polyphenols. Nuts are good sources of nutrient antioxidants. Nut extract, particularly walnut extract, has been shown to be neuroprotective against numerous stressors. Nuts contain various macronutrients and micronutrients, as well as bioactive phytochemicals with good health-promoting properties.