ABSTRACT

Dosimetry in bioelectromagnetics often refers to the means and procedures of calculating the amount of energy transferred to cell, tissue, and body. Biophysical stimulation" techniques can be used alone in clinical practice to increase and enhance reparative and anabolic activities of tissue, or they can be used in association with drugs, growth factors, to potentiate their activity and reduce side effects. This chapter focuses on the area of medicine dealing with physical agents with low-energy content, which we define as "clinical biophysics". Pharmacodynamics is fundamental for drug research and therapy development; similarly, clinical use of low-energy signals should be based on "physical dynamics": investigation of dose–response curves for the physical parameters characterizing the signals. The methods of biophysical stimulation used in clinical practice are: inductive (pulsed electromagnetic fields, PEMF), capacitive (capacitive coupled electrical field, CCEF), or mechanical (low-intensity pulsed ultrasound, LIPUS).