ABSTRACT
Infertility treatment has historically been related to multiple pregnancies because of the use of exogenous gonadotropins to stimulate follicular development in the ovary. Back in 1971, Atlay and Pennington described the incidence of multiple pregnancies in ovulation induction cycles in a series of 2369 pregnancies, from which 7.9% multiple pregnancies occurred: 6.9% twins, 0.5% triplets, 0.3% quadruplets, and 0.13% quintuplets (1).
