ABSTRACT

It is also important to keep in mind that the relative hydration of each prepackaged product varies. For instance, Juvederm and Restylane are not fully saturated, while Prevelle Silk is maximally saturated with water in the syringe. Due to the hydrophilic nature of HA, more concentrated and less saturated products will absorb more water initially, resulting in more swelling after injection, and maintain more hydration after an equilibrium is reached with surrounding tissue, resulting in more sustained fullness in the treated area. Thus, overcorrection is not recommended or necessary with HA ‘llers.