ABSTRACT

Abstract ................................................................................................. 220 13.1 Introduction .................................................................................. 220 13.2 Materials and Methods ................................................................. 221 13.3 Result and Discussions ................................................................ 224 13.4 Conclusion ................................................................................... 228 Keywords .............................................................................................. 229 References ............................................................................................. 229

ABSTRACT

Biocomposites are the composite materials which contain matrix phases formed by biopolymers. They are composed in such a manner that the final product can possess good biocompatibility. In the approach of implant coating and cellular recovery, the area of tissue engineering has resulted in a revolutionary change. The modern therapeutic technology has witnessed the biocomposites being successfully used for a variety of medical applications such as drug delivery, wound dressing and tissue regeneration. The highly porous polymer-ceramic composites can be applied as scaffold in tissue engineering. The major objective of this work is to fabricate a polyvinyl alcohol based composite with hydroxyapatite cross linked by glutaraldehyde. Characterization of the composites has been carried out by scanning electron microscopy, attenuated total reflection-Fourier transform infrared spectroscopy, swelling studies, X-ray diffraction and mechanical testing. The result of characterization denoted that the sample had a well-porous structure and could be applied for drug delivery.