ABSTRACT
The tripeptide glycyl-l-histadyl-l-lysine is primarily known as carrier peptides but has also been shown to have some signal peptide effects. Carrier peptides function to stabilize and deliver important trace elements necessary for wound healing and enzymatic processes. However, the neurotransmitter-affecting peptides currently incorporated into cosmeceutical products were developed as topical mimics of the botulinum neurotoxins. The topical neurotransmitter-affecting peptides that are currently marketed in cosmeceuticals reportedly function to decrease facial muscle contraction and thus reduce lines and wrinkles by raising the threshold for a minimal muscle activity, requiring more signals to achieve movement and reducing subconscious muscle movement over time. The advent of next-generation DNA- and RNA-sequencing technologies is poised to significantly impact the study of skin. Cosmeceutical peptides are a major player in the anti-aging market. The potential for new treatment option, as represented by cosmeceutical peptides, is a developing field with most ongoing research occurring within the industry.
