ABSTRACT
The scientific literature contains a substantial body of research addressing the toxicity and potential oncogenicity of radiofrequency radiation (RFR) in animal models. The chronic rodent oncogenicity bioassay is considered to be the "gold standard" protocol for the experimental assessment of carcinogenic activity. The largest chronic oncogenicity bioassay of RFR in rats was performed at IIT Research Institute under contract to the National Toxicology Program. A team of scientists at the University of Tubingen performed four small studies in female Sprague-Dawley rats to evaluate the possible oncogenicity of low-dose exposure to pulsed 900 MHz RFR with Global System For Mobile Communication modulation. The RFR exposure system used in the study was based on a reverberation chamber concept; details of the exposure system design and associated animal dosimetry have been published. Sham control and RFR-exposed rats demonstrated comparable survival, mean body weights, mean individual organ weights, and numbers and types of both neoplastic and non-neoplastic lesions.
